Folic acid,59-30-3
MK-4827 (HCl)
Folic acid
5-Bromo-2-chloropyrimidine 32779-36-5
Niraparib
(R)-tert-butyl 3-(4-aminophenyl)piperidine-1-carboxylate
(R)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate
tert-butyl 3-(4-aminophenyl)piperidine-1-carboxylate
![(3S)-3-[4-[7-[[(1,1-Dimethylethyl)amino]carbonyl]-2H-indazol-2-yl]phenyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester](/data/attachment/201705/26/3446bd2b841689a5afc36447418dc476.png "(3S)-3-[4-[7-[[(1,1-Dimethylethyl)amino]carbonyl]-2H-indazol-2-yl]phenyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester")
(3S)-3-[4-[7-[[(1,1-Dimethylethyl)amino]carbonyl]-2H-indazol-2-yl]phenyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
(3S)-3-(4-Bromophenyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
3-(4-Bromophenyl)piperidine-1-carboxylic acid tert-butyl ester
3-Chloro-4-(3-fluorobenzyloxy)nitrobenzene
Niraparib p-toluenesulfonate
![N-(1,1-Dimethylethyl)-2-[4-(3S)-3-piperidinylphenyl]-2H-indazole-7-carboxamide](/data/attachment/201705/26/da41ae70b523a458db70333bd1059362.png "N-(1,1-Dimethylethyl)-2-[4-(3S)-3-piperidinylphenyl]-2H-indazole-7-carboxamide")
N-(1,1-Dimethylethyl)-2-[4-(3S)-3-piperidinylphenyl]-2H-indazole-7-carboxamide
![2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide](/data/attachment/201705/26/d3114dd994f3dda3142cba7d326bcede.jpg "2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide")
2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
Alectinib
Benzaldehyde,4-(2-methylpropoxy)
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid
tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate
6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylic acid
![9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile](/data/attachment/201705/28/e48e5d316800efe6192ebfdeec6cf28c.gif "9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile")
9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
6-broMo-7-Methoxy-1,1-diMethyl-3,4-dihydronaphthalen-2(1H)-one
tert-butyl 4-(4-ethyl-3-iodophenyl)-4-methyl-3-oxopentanoate
![9-broMo-8-hydroxy-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile](/data/attachment/201705/28/fe98529212eb834b17a38f13138a35bf.png "9-broMo-8-hydroxy-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile")
9-broMo-8-hydroxy-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
![9-ethyl-6,6-diMethyl-8-(4-Morpholinopiperidin-1-yl)-11-oxo-5a,6,11,11a-tetrahydro-5H-benzo[b]carbazole-3-carbonitrile hydrochloride](/data/attachment/201705/28/36e5363f0c9f92378b75195743e2abb2.jpg "9-ethyl-6,6-diMethyl-8-(4-Morpholinopiperidin-1-yl)-11-oxo-5a,6,11,11a-tetrahydro-5H-benzo[b]carbazole-3-carbonitrile hydrochloride")
9-ethyl-6,6-diMethyl-8-(4-Morpholinopiperidin-1-yl)-11-oxo-5a,6,11,11a-tetrahydro-5H-benzo[b]carbazole-3-carbonitrile hydrochloride
tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate
ethyl 2-(4-broMophenyl)-2-Methylpropanoate
ert-Butyl (4R-cis)-6-formaldehydel-2,2-dimethyl-1,3-dioxane-4-acetate
(2S)-Hydroxy(phenyl)acetic acid (2R)-N-benzyl-1-(4-methoxyphenyl)propan-2-amine
5-Tosyladenosine
Filgotinib
3-amino-2-chloroacrolein
![2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxamide](/data/attachment/201706/03/2e19d959128718d26901f9909d7b9342.jpg "2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxamide")
2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxamide
![11-(1-Methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[d]iMidazo[1,2-a]azepine](/data/attachment/201706/03/1549d9affee63ead337049001f25d9fa.jpg "11-(1-Methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[d]iMidazo[1,2-a]azepine")
11-(1-Methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[d]iMidazo[1,2-a]azepine
1-(4-(1-PHENETHYL-1H-IMIDAZOLE-2-CARBONYL)PIPERIDIN-1-YL)ETHANONE
ethyl (3R)-5-amino-3-hydroxypentanoate,hydrochloride
LAS191954 free base
![tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate](/data/attachment/201706/03/8a3c0fcdeb9ed744fc854cf248d4d53e.jpg "tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate")
tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
ABT-494 Intermeidate N-2
ethyl (2E)-pent-2-enoate
abt594 Intermediate
LOXO101 Intermediate 2
LOXO101 Intermediate 1
Deutetrabenazine intermediate N-2
Deutetrabenazine intermediate N-1
Naldemedine tosylate intermediate
Naldemedine tosylate intermediate N-2
Naldemedine
Eribulin
![2-Furanpropanol, 5-[2-[(2S,4R,6R)-6-[[(2S,3S,4R,5R)-5-[(2S)-2,3-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]propyl]tetrahydro-4-methoxy-3-[(phenylsulfonyl) methyl]-2-furanyl]methyl]tetrahydro-4-methyl-5-methylene-2H-pyran-2-yl]ethyl]tetrahydro-4-methylene-,](/data/attachment/201706/03/3575f40dcc389832ca73cc99972a645b.gif.thumb.jpg "2-Furanpropanol, 5-[2-[(2S,4R,6R)-6-[[(2S,3S,4R,5R)-5-[(2S)-2,3-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]propyl]tetrahydro-4-methoxy-3-[(phenylsulfonyl) methyl]-2-furanyl]methyl]tetrahydro-4-methyl-5-methylene-2H-pyran-2-yl]ethyl]tetrahydro-4-methylene-,")
2-Furanpropanol, 5-[2-[(2S,4R,6R)-6-[[(2S,3S,4R,5R)-5-[(2S)-2,3-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]propyl]tetrahydro-4-methoxy-3-[(phenylsulfonyl) methyl]-2-furanyl]methyl]tetrahydro-4-methyl-5-methylene-2H-pyran-2-yl]ethyl]tetrahydro-4-methylene-,
2-BroMo-1-quinolin-6-yl-ethanone
![6-[(6-Bromo-1H-[1,2,3]triazolo[4,5-b]pyrazin-1-yl)methyl]-7-fluoroquinoline](/data/attachment/201706/07/27ae4307b53f4294590fb8f914894490.jpg "6-[(6-Bromo-1H-[1,2,3]triazolo[4,5-b]pyrazin-1-yl)methyl]-7-fluoroquinoline")
6-[(6-Bromo-1H-[1,2,3]triazolo[4,5-b]pyrazin-1-yl)methyl]-7-fluoroquinoline
tert-butyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate
![7-Trifluoromethyl-imidazo[1,2-a]pyridine](/data/attachment/201706/07/24ba6100528abe0753ad9e82ef8dc810.gif "7-Trifluoromethyl-imidazo[1,2-a]pyridine")
7-Trifluoromethyl-imidazo[1,2-a]pyridine
methyl 4-(aminomethyl)-3-chlorobenzoate
methyl 3-oxo-2-(trifluoromethyl)butanoate
![2-AMino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid tert-butyl ester](/data/attachment/201706/07/22aadd4c55094254a681014935f56827.jpg "2-AMino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid tert-butyl ester")
2-AMino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid tert-butyl ester
2(1H)-Quinolinone, 3,4-dihydro-3,3-dimethyl
Methanone, (2-aMino-5-Methoxyphenyl)(4-chlorophenyl)
benzyl 5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylate
3-(1H-pyrazol-5-yl)phenol
4-(1H-Pyrazol-3-yl)aniline
1-(5-bromo-pyridin-2-yl)-2,2-dimethyl-propan-1-ol
1-(5-bromo-pyridin-2-yl)-2-methyl-propan-1-ol
![Benzenemethanol, a-[(1S)-1-aminoethyl]-4-hydroxy-,(aR)](/data/attachment/201706/07/c4adcbada0ef372ae46cbaed643dd18e.jpg "Benzenemethanol, a-[(1S)-1-aminoethyl]-4-hydroxy-,(aR)")
Benzenemethanol, a-[(1S)-1-aminoethyl]-4-hydroxy-,(aR)
![2(1H)-Quinolinone,5-[(1R)-2-amino-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-8-hydroxy](/data/attachment/201706/07/e0e9b5769a45af836d70be4140043125.gif.thumb.jpg "2(1H)-Quinolinone,5-[(1R)-2-amino-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-8-hydroxy")
2(1H)-Quinolinone,5-[(1R)-2-amino-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-8-hydroxy
![2-{[3-(4-Fluorophenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrim idin-2-yl]sulfanyl}-N-(6-methyl-1,3-benzothiazol-2-yl)acetamide](/data/attachment/201706/07/5754ee36bdfbf4148f45632422f563b9.jpg "2-{[3-(4-Fluorophenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrim idin-2-yl]sulfanyl}-N-(6-methyl-1,3-benzothiazol-2-yl)acetamide")
2-{[3-(4-Fluorophenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrim idin-2-yl]sulfanyl}-N-(6-methyl-1,3-benzothiazol-2-yl)acetamide
![2-((3-(2-methoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide](/data/attachment/201706/08/47a8b3c98aef0b9ba378c4b7c6cef435.jpg "2-((3-(2-methoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide")
2-((3-(2-methoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide
![N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide](/data/attachment/201706/08/beda6f8f4655aa74d3646cfc7621fb20.jpg "N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide")
N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
(R)-(-)-1-(4-methoxyphenyl)-2-benzylaminopropane
![4(3H)-Quinazolinone,7-bromo-6-chloro-3-[3-(3-hydroxy-2-piperidinyl)-2-oxopropyl]](/data/attachment/201706/09/b600ffca12695094db2c5f6045cb6685.jpg "4(3H)-Quinazolinone,7-bromo-6-chloro-3-[3-(3-hydroxy-2-piperidinyl)-2-oxopropyl]")
4(3H)-Quinazolinone,7-bromo-6-chloro-3-[3-(3-hydroxy-2-piperidinyl)-2-oxopropyl]
![9-OXO-1,2,3,9-TETRAHYDRO-PYRROLO[2,1-B]QUINAZOLINE-6-CARBOXYLIC ACID](/data/attachment/201706/09/d6b395bbfb23e628be7d536d9cc2b512.gif "9-OXO-1,2,3,9-TETRAHYDRO-PYRROLO[2,1-B]QUINAZOLINE-6-CARBOXYLIC ACID")
9-OXO-1,2,3,9-TETRAHYDRO-PYRROLO[2,1-B]QUINAZOLINE-6-CARBOXYLIC ACID
Alanine, 2-methyl-, phenylmethyl ester
2-(2-TRIFLUOROMETHYL-PHENYL)-PYRROLIDINE
(-)-4(R)-(2-Chloro-4-fluorophenyl)-2-(3,5-difluoropyridin-2-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxylic acid methyl ester
![2-Butenoic acid, 2-hydroxy-4-[5-(1-Methylethyl)-2,4-bis(phenylMethoxy)phenyl]-4-oxo-, ethyl ester](/data/attachment/201706/09/11c6e17ba89840528c5461ae5350df33.gif "2-Butenoic acid, 2-hydroxy-4-[5-(1-Methylethyl)-2,4-bis(phenylMethoxy)phenyl]-4-oxo-, ethyl ester")
2-Butenoic acid, 2-hydroxy-4-[5-(1-Methylethyl)-2,4-bis(phenylMethoxy)phenyl]-4-oxo-, ethyl ester
methanone](/data/attachment/201706/09/ca947be16560699c92609cd96b352c02.png.thumb.jpg "[4-amino-2-(ethylsulfanyl)pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone")
[4-amino-2-(ethylsulfanyl)pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone
![Benzenesulfonamide, 2-[(5-bromo-2-chloro-4-pyrimidinyl)amino]-N-methyl](/data/attachment/201706/10/ce0d621896c03bdb67e3b184103e84ff.png.thumb.jpg "Benzenesulfonamide, 2-[(5-bromo-2-chloro-4-pyrimidinyl)amino]-N-methyl")
Benzenesulfonamide, 2-[(5-bromo-2-chloro-4-pyrimidinyl)amino]-N-methyl
ALK inhibitor 2
Cefmenoxime hydrochloride
(S)-N-1-Boc-N-4-Cbz-2-piperazinecarboxylic acid
Avermectin
L-CANAVANINE SULFATE
3-Fluoropropiophenone 455-67-4
3-Hydroxypropiophenone 13103-80-5
2-Cyano-5-chloropyrimidine 38275-56-8
N-Formylpiperidine 2591-86-8
Indazole-3-carboxylic acid 4498-67-3
5-Bromo-2-cyanopyrimidine 38275-57-9
4,4-Dibromobenzophenone 3988-03-2
![1,2,3,4-Tetrahydro-benzo[b]azepin-5-one 1127-74-8](/data/attachment/201901/28/b183df1e648eca4396ad0d319a1254bc.jpg "1,2,3,4-Tetrahydro-benzo[b]azepin-5-one 1127-74-8")
1,2,3,4-Tetrahydro-benzo[b]azepin-5-one 1127-74-8
4038-14-6,(3,4-dimethoxyphenyl)-phenylmethanone 4038-14-6
2-Amino-5-bromopyrimidine 7752-82-1
Triphenylbismuth 603-33-8
![3-Ethynylimidazo[1,2-a]pyridine 943320-53-4](/data/attachment/201901/28/d6294d1dabcee85ee04792b0c0e255c0.jpg "3-Ethynylimidazo[1,2-a]pyridine 943320-53-4")
3-Ethynylimidazo[1,2-a]pyridine 943320-53-4
4-Nitrophenylacetonitrile 555-21-5
2-(4-aminophenyl)acetonitrile 3544-25-0
isoxazole 288-14-2
5-Methylisoxazole 5765-44-6
3-Aminoisoxazole 1750-42-1
2-Hydroxydiphenylmethane 28994-41-4
2,5-Difluorobenzyl Cyanide 69584-87-8
2,4-Difluorophenylacetonitrile 656-35-9
2,5-Difluorophenylacetic acid 85068-27-5
2,4-Difluorophenylacetic acid 81228-09-3
3-trifluoromethylbenzoic acid 454-92-2
![2-[3-(trifluoromethyl)phenyl]acetonitrile 2338-76-3](/data/attachment/201901/29/22b99245cb0bbcd2d86f238725d9fb9d.jpg "2-[3-(trifluoromethyl)phenyl]acetonitrile 2338-76-3")
2-[3-(trifluoromethyl)phenyl]acetonitrile 2338-76-3
![2-[3-(trifluoromethyl)phenyl]acetic acid 351-35-9](/data/attachment/201901/29/7dbc74a276a4c124b9460222442fd80f.jpg "2-[3-(trifluoromethyl)phenyl]acetic acid 351-35-9")
2-[3-(trifluoromethyl)phenyl]acetic acid 351-35-9
3-Chlorobenzoyl chloride 618-46-2
3-Chlorobenzaldehyde 587-04-2
3-chlorobenzoic acid 535-80-8
3-Chlorobenzyl chloride 620-20-2
3-Chlorobenzyl cyanide 1529-41-5
2-(3-chlorophenyl)acetic acid 1878-65-5
Dimethylchloroacetal 97-97-2
Chloroacetaldehyde diethyl acetal 621-62-5
2-bromo-1,1-diethoxyethane 2032-35-1
2,2-dimethoxyethanamine 22483-09-6
2,2-Diethoxyethylamine 645-36-3
2-Methylphenylacetic acid 644-36-0
3-Isochromanone 4385-35-7
2,5-Dimethylphenylacetic acid 13612-34-5
2,4-Dimethylphenylacetic Acid 6331-04-0
2,5-Dimethylphenylacetonitrile 16213-85-7
2,4-Dimethylphenylacetonitrile 68429-53-8
5-CHLORO-2-FLUOROBENZOYL CHLORIDE 394-29-6
5-Chloro-2-fluorobenzoic acid 394-30-9
2,5-Dichlorobenzaldehyde 6361-23-5
2,5-Dichlorobenzoic acid 50-79-3
2,5-DICHLOROBENZOYL CHLORIDE 2905-61-5
2,2-Azobis(2-methylpropionamidine) dihydrochloride 2997-92-4
L-Phenylalanine, 1-methylethyl ester, hydrochloride 95585-78-7
Diphenylphosphoryl azide 26386-88-9
Methyl 4-(bromomethyl)benzoate 2417-72-3
Tideglusib 865854-05-3
Disodium 7,7-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate) 20324-87-2
SU 6656 330161-87-0
Saccharin 1-methylimidazole 482333-74-4
CeMMEC13 1790895-25-8
Rabusertib 911222-45-2
Salermide 1105698-15-4
EST 88321-09-9
SC79 305834-79-1
C646 328968-36-1
1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea 182498-32-4
Dp44mT 152095-12-0
Deguelin 522-17-8
PD168393 194423-15-9
YO01027 209984-56-5
DC10539 1822358-25-7
8-OH-DPAT 78950-78-4
YU238259 1943733-16-1
Scriptaid 287383-59-9
Velpatasvir 1377049-84-7
OTX015 202590-98-5
(+)-JQ-1 1268524-70-4
(-)-JQ-1 1268524-71-5
LY 900009 209984-68-9
LY-411575 209984-57-6
![(4-nitrophenyl) 4-[bis(1,3-benzodioxol-5-yl)-hydroxymethyl]piperidine-1-carboxylate 1101854-58-3](/data/attachment/201903/22/9e81dae7e0bdec56ac6052b1872d9626.jpg "(4-nitrophenyl) 4-[bis(1,3-benzodioxol-5-yl)-hydroxymethyl]piperidine-1-carboxylate 1101854-58-3")
(4-nitrophenyl) 4-[bis(1,3-benzodioxol-5-yl)-hydroxymethyl]piperidine-1-carboxylate 1101854-58-3
N,N-dimethyl-2-oxo-1,3-dihydroindole-5-sulfonamide 170565-89-6
![5,6,11,12-tetrahydrodibenzo[1,2-b:1,2-g][8]annulene 1460-59-9](/data/attachment/201903/23/50930df6d55412ac8f4da0724b497aaf.jpg "5,6,11,12-tetrahydrodibenzo[1,2-b:1,2-g][8]annulene 1460-59-9")
5,6,11,12-tetrahydrodibenzo[1,2-b:1,2-g][8]annulene 1460-59-9
Tetraphenylmethane 630-76-2
![2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile 284035-33-2](/data/attachment/201903/23/7e63bafe6c4b7e146e00c57dfca99672.jpg "2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile 284035-33-2")
2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile 284035-33-2
1616380-54-1
![N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide 440662-09-9](/data/attachment/201903/23/e26baac537719657acd9f1f55568401d.jpg "N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide 440662-09-9")
N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide 440662-09-9
![N-[2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]ethyl]butanamide 932986-18-0](/data/attachment/201903/23/7d2bbd100c8322ae16168937617e1bb2.jpg "N-[2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]ethyl]butanamide 932986-18-0")
N-[2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]ethyl]butanamide 932986-18-0
5-(5-(2-(3-aminopropoxy)-6-methoxyphenyl)-1H-pyrazol-3-ylamino)pyrazine-2-carbonitrile 1234015-52-1
![3-Methyl-3-[(1E)-2-phenylethenyl]-3,2:5,2:5,3-quaterpyridine 1651890-44-6](/data/attachment/201903/23/07bf6fd99e81033df0c83039ccdde036.jpg "3-Methyl-3-[(1E)-2-phenylethenyl]-3,2:5,2:5,3-quaterpyridine 1651890-44-6")
3-Methyl-3-[(1E)-2-phenylethenyl]-3,2:5,2:5,3-quaterpyridine 1651890-44-6
![3-[4-(Dimethylamino)-3-biphenylyl]-1,1-dimethylure 1469924-27-3](/data/attachment/201903/23/f69ad7342d131146640e0c88f73e9a25.jpg "3-[4-(Dimethylamino)-3-biphenylyl]-1,1-dimethylure 1469924-27-3")
3-[4-(Dimethylamino)-3-biphenylyl]-1,1-dimethylure 1469924-27-3
8-Methoxy-N,N-dipropyl-1,2,3,4-tetrahydro-2-naphthalenamine 3897-94-7
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benzocaine 94-09-7
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lidocaine 137-58-6
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Bis(4-methylphenyl)methanol 885-77-8
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EP-Directory listing
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EP-Directory listing 2
EP-Directory listing 3
| Name: | 22373-78-0 Monensin sodium salt |
| CAS No: | 22373-78-0 |
 | |
| Monensin sodium salt Basic information |
| Product Name: | Monensin sodium salt |
| Synonyms: | Coban45;gamma,2,8-tetramethyl--furyl)-2-furyl)-9-hydroxy-beta-methoxy-alphmonosod;methyl-5-(tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2h-pyran-2-yl)-2;monensin,monosodiumsalt;Monensin,monosodiumsalt(9CI);Previouscas:22136-43-2;Sodiummonensin;2-[5-Ethyltetrahydro-5-[tetrahydro-3-Methyl-5-[tetrahydro-6-hydroxy-6-(hydroxyMethyl)-3,5-diMethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-Methoxy-α,γ,2,8-tetraMethyl- |
| CAS: | 22373-78-0 |
| MF: | C36H63NaO12 |
| MW: | 710.87 |
| EINECS: | 244-941-7 |
| Product Categories: | Inhibitors;Organics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol File: | 22373-78-0.mol |
 |
|
| Monensin sodium salt Chemical Properties |
| Melting point | 267-269 C |
| alpha | 57.3 º (c=4.0, in MeOH) |
| storage temp. | 2-8°C |
| solubility | Soluble in methanol at 50mg/ml |
| form | Off-white to beige solid |
| color | White |
| BRN | 4122200 |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. |
| InChIKey | XOIQMTLWECTKJL-BEMBKCOJSA-M |
| EPA Substance Registry System | Monensin, monosodium salt (22373-78-0) |
| Safety Information |
| Hazard Codes | T,T+ |
| Risk Statements | 25-26/27/28 |
| Safety Statements | 36/37/39-45-22 |
| RIDADR | UN 3462 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | JH2830000 |
| HazardClass | 6.1(a) |
| PackingGroup | II |
| HS Code | 29419090 |
| MSDS Information |
| Provider | Language |
|---|---|
| Monensin sodium salt | English |
| Monensin sodium salt Usage And Synthesis |
| Description | Monensin is a naturally occuring ionophorous antibiotic that preferentially forms complexes with monovalent cations to enable transport across lipid membranes. Through its ability to affect pH and the sodium-potassium balance of a cell, monensin can induce cell death in Gram-positive bacteria such as Micrococcus, Bacillus, and Staphylococcus (MICs = 1-12.5 μg/ml), reduce proliferation of P. falciparum and Coccicdium protozoa, and also prevent replication of certain viruses. |
| Chemical Properties | LIGHT CREAM AMORPHOUS POWDER |
| Uses | Poliether antibiotic. Coccidiostat. |
| Uses | antifungal |
| Uses | antibacterial |
| Uses | Monensin sodium salt is used in potentiometric and spectroscopic studies of alkali metal ion complexes. Monensin (Na) is a polyether small molecule ionophore, capable of forming stable complexes to monovalent cations with specific affinity for Na+. Monensin presents a highly lipophilic scaffold around the bound ion, allowing movement of the complex through the lipid bilayer and consequent transport of the ion out of the cell. Excessive flux of ions out of the cell produces a cytotoxic effect and generates the antibiotic properties of Monensin. |
| General Description | Monensin is a polyether ionophoric antibiotic, which is produced by Streptomyces cinnamonensis. It is used to treat bacterial, fungal and parasitic infections. Monensin prevents the growth of colon cancer cells. It facilitates the transport of sodium and potassium ions between intracellular and extracellular spaces. Monensin prevents coccidiosis?in poultry production. |
| Biochem/physiol Actions | Na+ ionophore; blocks glycoprotein secretion; may induce catecholamine secretion from chromaffin cells. Useful in potentiometric and spectroscopic studies of alkali metal ion complexes. |
| Purification Methods | Crystallise it from EtOH/H2O [Cox et al. J Am Chem Soc 107 4297 1985]. |
| References | Aowicki and Huczynski (2013), Structure and antimicrobial properties of monensin A and its derivatives: summary of the achievements; Res. Int. 2013 742149 Kallen et al. (1993), Monensin inhibits synthesis of plasma membrane sphingomyelin by blocking transport of ceramide through the Golgi: evidence for two sites of sphingomyelin synthesis in BHK cells; Biophys. Acta 1166 305 Boss et al. (1984), Monensin-induced swelling of Golgi apparatus cisternae mediated by a proton gradient; J. Cell. Biol. 34 1 Mollenhauer et al. (1990), Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity; Biophys. Acta 1031 225 Hafner et al. (2021), The Cardenolide Glycoside Acovenoside A Interferes with Epidermal Growth Factor Receptor Trafficking in Non-Small Cell Lung Cancer Cells; Pharmacol. 12 611657 Oh-Hashi et al. (2021), Comparative Analysis of CREB3 and CREB3L2 Protein Expression in HEK293 Cells; J. Mol. Sci. 22 2767 |
| Monensin sodium salt Preparation Products And Raw materials |
| Preparation Products | Monensin |
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