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  • N-methyl-N-[2-[[[2-[(2-oxo-1,3-dihydroindol-5-yl  717906-29-1
Name:N-methyl-N-[2-[[[2-[(2-oxo-1,3-dihydroindol-5-yl 717906-29-1
CAS No:717906-29-1

PRODUCT DESCRIPTION


Description

PF 431396 is a dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor (IC50 values are 2 and 11 nM respectively). Promotes osteoblast recruitment and activity, and stimulates bone formation in ovariectomized rats.

Basic Info

Chemical Name N-methyl-N-[2-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide
Synonyms

3fzr;N-METHYL-N-[2-[[[2-[(2-OXO-2,3-DIHYDRO-1H-INDOL-5-YL)AMINO]-5-TRIFLUOROMETHYLPYRIMIDIN-4-YL]AMINO]METHYL]PHENYL]METHANESULFONAMIDE;

CAS No. 717906-29-1
Molecular Formula C22H21F3N6O3S
Molecular Weight 506.50100
PSA 127.93000
LogP 4.45520

Numbering system

MDL number MFCD16038300

Properties

Density 1.506

Safety Info

Symbol GHS06
Caution Statement P301 + P310; P305 + P351 + P338
Signal Word Danger
Hazard Declaration H301; H319

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