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  • Methyl 2-​chloro-​4-​(trifluoromethyl)​pyrimidine-​5-​carboxylate  175137-27-6
Name:Methyl 2-​chloro-​4-​(trifluoromethyl)​pyrimidine-​5-​carboxylate 175137-27-6
CAS No:175137-27-6

PRODUCT DESCRIPTION


Description

Methyl 2-Chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate is used in the synthetic preparation and discovery of 2-[(2,4-Dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide which is a highly selective CB2 receptor agonist for the treatment of inflammatory and neuropathic pain.

Basic Info

Chemical Name Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate
Synonyms

Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate;

CAS No. 175137-27-6
Molecular Formula C7H4ClF3N2O2
Molecular Weight 240.56700
PSA 52.08000
LogP 1.93540

Properties

Density 1.366g/cm3
Boiling Point 76-78ºC 0,5mm
Melting Point 253-254ºC
Flash Point 163.7ºC
Refractive Index 1.502
Vapor Pressure 5.54E-05mmHg at 25°C

Safety Info

Safety Statements S23-S26-S36/37/39
HS Code 2933599090
Risk Statements R20/21/22; R36/37/38
Hazard Codes Xn
Caution Statement P261; P301 + P310; P305 + P351 + P338
Hazard Declaration H301; H315; H319; H335
Signal Word Danger
Symbol GHS06

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