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  • zolmitriptan  139264-17-8
Name:zolmitriptan 139264-17-8
CAS No:139264-17-8

PRODUCT DESCRIPTION


Description

Zolmitriptan is a selective serotonin receptor agonist of the 1B and 1D subtypes. It is a triptan, used in the acute treatment of migraine attacks with or without aura and cluster headaches.
Zolmitriptan is marketed by AstraZeneca with the brand names Zomig, Zomigon (Argentina, Canada & Greece), AscoTop (Germany) and Zomigoro (France). In 2008, Zomig generated nearly $154 million in sales.
AstraZeneca's U.S. patent on Zomig tablets expired on November 14, 2012, and its pediatric exclusivity extension expired on May 14, 2013. The patent in certain European countries has already expired too, and generic drug maker Actavis released a generic version in those countries, starting in March 2012.

Basic Info

Chemical Name zolmitriptan
Synonyms

(S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone;Zolmitriptan;(4R)-4-[[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one;

CAS No. 139264-17-8
Molecular Formula C16H21N3O2
Molecular Weight 287.35700
PSA 57.36000
LogP 2.25170

Properties

Appearance & Physical State White or kind of white powder
Density 1.217 g/cm3
Boiling Point 563.3ºC at 760 mmHg
Melting Point 136-141ºC
Flash Point 294.5ºC
Refractive Index 1.619
Storage Condition Store in original container in a cool dark place.
Vapor Pressure 1.03E-12mmHg at 25°C

Safety Info

Safety Statements S26-S36
HS Code 2934999090
Risk Statements R36/37/38
Hazard Codes Xi

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