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  • lurasidone  367514-87-2
Name:lurasidone 367514-87-2
CAS No:367514-87-2

PRODUCT DESCRIPTION

lurasidone

CAS No.: 367514-87-2
Synonyms:
    Formula: C28H36N4O2S
    Exact Mass: 492.25600
    Molecular Weight: 492.67600
    PSA: 84.99000
    LogP: 4.19660
    DescriptionFeedback
    Lurasidone (trade name Latuda) is an atypical antipsychotic developed by Dainippon Sumitomo Pharma and marketed by Sunovion in the USA. In the USA since 2013, it is also approved for the treatment of depressive episodes associated with bipolar I disorder as well as bipolar II disorder in adults when used alone or in combination with lithium, valproate, or lamotrigine.



























    SAFETY DATA SHEETS

    According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

    Version: 1.0

    Creation Date: Aug 16, 2017

    Revision Date: Aug 16, 2017

    1.Identification

    1.1GHS Product identifier

    Product name lurasidone

    1.2Other means of identification

    Product number -
    Other names -

    1.3Recommended use of the chemical and restrictions on use

    Identified uses For industry use only.
    Uses advised against no data available

    1.4Supplier's details

    Company XiXisys.com
    Address XiXisys.com
    Telephone XiXisys.com
    Fax XiXisys.com

    1.5Emergency phone number

    Emergency phone number -
    Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

    2.Hazard identification

    2.1Classification of the substance or mixture

    Acute toxicity - Oral, Category 4

    Skin sensitization, Category 1

    Acute toxicity - Inhalation, Category 4

    Reproductive toxicity, Category 2

    2.2GHS label elements, including precautionary statements

    Pictogram(s)  
    Signal word

    Warning

    Hazard statement(s)

    H302+H332 Harmful if swallowed or if inhaled

    H317 May cause an allergic skin reaction

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P272 Contaminated work clothing should not be allowed out of the workplace.

    P280 Wear protective gloves/protective clothing/eye protection/face protection.

    P271 Use only outdoors or in a well-ventilated area.

    P201 Obtain special instructions before use.

    P202 Do not handle until all safety precautions have been read and understood.

    Response

    P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/…if you feel unwell.

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P333+P313 If skin irritation or rash occurs: Get medical advice/attention.

    P321 Specific treatment (see ... on this label).

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P312 Call a POISON CENTER/doctor/…if you feel unwell.

    P308+P313 IF exposed or concerned: Get medical advice/ attention.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to ...

    2.3Other hazards which do not result in classification

    none

    3.Composition/information on ingredients

    3.1Substances

    Chemical name Common names and synonyms CAS number EC number Concentration
    lurasidone lurasidone 367514-87-2 none 100%

    4.First-aid measures

    4.1Description of necessary first-aid measures

    General advice

    Consult a physician. Show this safety data sheet to the doctor in attendance.

    If inhaled

    If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

    In case of skin contact

    Wash off with soap and plenty of water. Consult a physician.

    In case of eye contact

    Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

    If swallowed

    Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

    4.2Most important symptoms/effects, acute and delayed

    no data available

    4.3Indication of immediate medical attention and special treatment needed, if necessary

    no data available

    5.Fire-fighting measures

    5.1Extinguishing media

    Suitable extinguishing media

    Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

    5.2Specific hazards arising from the chemical

    no data available

    5.3Special protective actions for fire-fighters

    Wear self-contained breathing apparatus for firefighting if necessary.

    6.Accidental release measures

    6.1Personal precautions, protective equipment and emergency procedures

    Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

    6.2Environmental precautions

    Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

    6.3Methods and materials for containment and cleaning up

    Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

    7.Handling and storage

    7.1Precautions for safe handling

    Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

    7.2Conditions for safe storage, including any incompatibilities

    Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

    8.Exposure controls/personal protection

    8.1Control parameters

    Occupational Exposure limit values

    no data available

    Biological limit values

    no data available

    8.2Appropriate engineering controls

    Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

    8.3Individual protection measures, such as personal protective equipment (PPE)

    Eye/face protection

    Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

    Skin protection

    Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

    Respiratory protection

    Wear dust mask when handling large quantities.

    Thermal hazards

    no data available

    9.Physical and chemical properties

    Physical state no data available
    Colour no data available
    Odour no data available
    Melting point/ freezing point no data available
    Boiling point or initial boiling point and boiling range no data available
    Flammability no data available
    Lower and upper explosion limit / flammability limit no data available
    Flash point no data available
    Auto-ignition temperature no data available
    Decomposition temperature no data available
    pH no data available
    Kinematic viscosity no data available
    Solubility no data available
    Partition coefficient n-octanol/water (log value) no data available
    Vapour pressure no data available
    Density and/or relative density no data available
    Relative vapour density no data available
    Particle characteristics no data available

    10.Stability and reactivity

    10.1Reactivity

    no data available

    10.2Chemical stability

    Stable under recommended storage conditions.

    10.3Possibility of hazardous reactions

    no data available

    10.4Conditions to avoid

    no data available

    10.5Incompatible materials

    no data available

    10.6Hazardous decomposition products

    no data available

    11.Toxicological information

    Acute toxicity

    • Oral: no data available
    • Inhalation: no data available
    • Dermal: no data available

    Skin corrosion/irritation

    no data available

    Serious eye damage/irritation

    no data available

    Respiratory or skin sensitization

    no data available

    Germ cell mutagenicity

    no data available

    Carcinogenicity

    no data available

    Reproductive toxicity

    no data available

    STOT-single exposure

    no data available

    STOT-repeated exposure

    no data available

    Aspiration hazard

    no data available

    12.Ecological information

    12.1Toxicity

    • Toxicity to fish: no data available
    • Toxicity to daphnia and other aquatic invertebrates: no data available
    • Toxicity to algae: no data available
    • Toxicity to microorganisms: no data available

    12.2Persistence and degradability

    no data available

    12.3Bioaccumulative potential

    no data available

    12.4Mobility in soil

    no data available

    12.5Other adverse effects

    no data available

    13.Disposal considerations

    13.1Disposal methods

    Product

    The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

    Contaminated packaging

    Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

    14.Transport information

    14.1UN Number

    ADR/RID: no data available IMDG: no data available IATA: no data available

    14.2UN Proper Shipping Name

    ADR/RID: no data available
    IMDG: no data available
    IATA: no data available

    14.3Transport hazard class(es)

    ADR/RID: no data available IMDG: no data available IATA: no data available

    14.4Packing group, if applicable

    ADR/RID: no data available IMDG: no data available IATA: no data available

    14.5Environmental hazards

    ADR/RID: no IMDG: no IATA: no

    14.6Special precautions for user

    no data available

    14.7Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

    no data available

    15.Regulatory information

    15.1Safety, health and environmental regulations specific for the product in question

    Chemical name Common names and synonyms CAS number EC number
    lurasidone lurasidone 367514-87-2 none
    European Inventory of Existing Commercial Chemical Substances (EINECS) Not Listed.
    EC Inventory Not Listed.
    United States Toxic Substances Control Act (TSCA) Inventory Not Listed.
    China Catalog of Hazardous chemicals 2015 Not Listed.
    New Zealand Inventory of Chemicals (NZIoC) Not Listed.
    Philippines Inventory of Chemicals and Chemical Substances (PICCS) Not Listed.
    Vietnam National Chemical Inventory Not Listed.
    Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Not Listed.

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