FRIDAY, Feb. 15, 2019 -- For patients with an admitting diagnosis of acute coronary syndrome and/or acute decompensated heart failure, opioid prescription at discharge is not significantly associated with unplanned health care utilization or mortality but is associated with reduced odds of completed planned health care utilization, according to a study published in the Feb. 5 issue of the Journal of the American Heart Association.
Justin S. Liberman, M.D., M.P.H., from the Veterans Health Administration Valley VA Health Care System Geriatric Research Education Clinical Center in Nashville, Tennessee, and colleagues performed a nested evaluation involving 3,000 patients from the Vanderbilt Inpatient Cohort Study with an admitting diagnosis of acute coronary syndrome and/or acute decompensated heart failure. Twenty percent of the 2,495 eligible patients were discharged with an opioid prescription.
The researchers found no significant association between discharge with an opioid prescription and increased unplanned health care utilization (adjusted hazard ratio, 1.06; 95 percent confidence interval, 0.87 to 1.28) or mortality (adjusted hazard ratio, 1.08; 95 percent confidence interval, 0.84 to 1.39) compared with those not prescribed opioids at discharge. The likelihood of completing planned health care utilization was reduced for patients discharged with opioids (adjusted odds ratio, 0.69; 95 percent confidence interval, 0.52 to 0.91).
"Our study supports reductions in opioid prescriptions to improve planned health care utilization behaviors," the authors write. "Further research is necessary to understand opioid use and its association with patient self-care to improve clinical outcomes."
1127-74-8,1,2,3,4-Tetrahydro-benzo[b]azepin-5-one
Read More4038-14-6,(3,4-dimethoxyphenyl)-phenylmethanone
Read More2338-76-3,2-[3-(trifluoromethyl)phenyl]acetonitrile
Read More351-35-9,2-[3-(trifluoromethyl)phenyl]acetic acid
Read More2997-92-4,2,2'-Azobis(2-methylpropionamidine) dihydrochloride
Read More95585-78-7,L-Phenylalanine, 1-methylethyl ester, hydrochloride
Read More20324-87-2,Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate)
Read More182498-32-4,1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea
Read More1101854-58-3,(4-nitrophenyl) 4-[bis(1,3-benzodioxol-5-yl)-hydroxymethyl]piperidine-1-carboxylate
Read More170565-89-6,N,N-dimethyl-2-oxo-1,3-dihydroindole-5-sulfonamide
Read More1460-59-9,5,6,11,12-tetrahydrodibenzo[1,2-b:1',2'-g][8]annulene
Read More284035-33-2,2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile
Read More440662-09-9,N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide
Read More932986-18-0,N-[2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]ethyl]butanamide
Read More1234015-52-1,5-(5-(2-(3-aminopropoxy)-6-methoxyphenyl)-1H-pyrazol-3-ylamino)pyrazine-2-carbonitrile
Read More1651890-44-6,3'-Methyl-3''-[(1E)-2-phenylethenyl]-3,2':5',2'':5'',3'''-quaterpyridine
Read More1469924-27-3,3-[4'-(Dimethylamino)-3-biphenylyl]-1,1-dimethylure
Read More3897-94-7,8-Methoxy-N,N-dipropyl-1,2,3,4-tetrahydro-2-naphthalenamine
Read More1202759-32-7,4-{4-[(4-{[3-(Acryloylamino)phenyl]amino}-5-fluoro-2-pyrimidinyl) amino]phenoxy}-N-methyl-2-pyridinecarboxamide
Read More71145-03-4,1,4-Dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)-pyridine-5-carboxylic acid methyl ester
Read More500579-04-4,2-[[3-[[2-(dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N,N-dimethylaniline
Read More1443437-74-8,N-(4-chlorophenyl)-1-(3-(furan-2-yl)benzoyl)piperidine-3-carboxamide
Read More1125-29-7 1,3,5-Trimethyl-1H-pyrazole-4-carboxylic acid
Read More23362-56-3 [2-(aminocarbonyl)phenyl]acetic acid
Read More103788-65-4 2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethan-1-ol
Read More120503-69-7 2-Amino-6-cyclopropylamino-9H-purine
Read More