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tert-butyl 3-(4-aminophenyl)piperidine-1-carboxylate
(3S)-3-[4-[7-[[(1,1-Dimethylethyl)amino]carbonyl]-2H-indazol-2-yl]phenyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
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3-(4-Bromophenyl)piperidine-1-carboxylic acid tert-butyl ester
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N-(1,1-Dimethylethyl)-2-[4-(3S)-3-piperidinylphenyl]-2H-indazole-7-carboxamide
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2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid
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6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylic acid
9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
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ethyl 2-(4-broMophenyl)-2-Methylpropanoate
ert-Butyl (4R-cis)-6-formaldehydel-2,2-dimethyl-1,3-dioxane-4-acetate
(2S)-Hydroxy(phenyl)acetic acid (2R)-N-benzyl-1-(4-methoxyphenyl)propan-2-amine
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ABT-494 Intermeidate N-2
ethyl (2E)-pent-2-enoate
abt594 Intermediate
LOXO101 Intermediate 2
LOXO101 Intermediate 1
Deutetrabenazine intermediate N-2
Deutetrabenazine intermediate N-1
Naldemedine tosylate intermediate
Naldemedine tosylate intermediate N-2
Naldemedine
Eribulin
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2-BroMo-1-quinolin-6-yl-ethanone
6-[(6-Bromo-1H-[1,2,3]triazolo[4,5-b]pyrazin-1-yl)methyl]-7-fluoroquinoline
tert-butyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate
7-Trifluoromethyl-imidazo[1,2-a]pyridine
methyl 4-(aminomethyl)-3-chlorobenzoate
methyl 3-oxo-2-(trifluoromethyl)butanoate
2-AMino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid tert-butyl ester
2(1H)-Quinolinone, 3,4-dihydro-3,3-dimethyl
Methanone, (2-aMino-5-Methoxyphenyl)(4-chlorophenyl)
benzyl 5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylate
3-(1H-pyrazol-5-yl)phenol
4-(1H-Pyrazol-3-yl)aniline
1-(5-bromo-pyridin-2-yl)-2,2-dimethyl-propan-1-ol
1-(5-bromo-pyridin-2-yl)-2-methyl-propan-1-ol
Benzenemethanol, a-[(1S)-1-aminoethyl]-4-hydroxy-,(aR)
2(1H)-Quinolinone,5-[(1R)-2-amino-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-8-hydroxy
2-{[3-(4-Fluorophenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrim idin-2-yl]sulfanyl}-N-(6-methyl-1,3-benzothiazol-2-yl)acetamide
2-((3-(2-methoxyphenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide
N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
(R)-(-)-1-(4-methoxyphenyl)-2-benzylaminopropane
4(3H)-Quinazolinone,7-bromo-6-chloro-3-[3-(3-hydroxy-2-piperidinyl)-2-oxopropyl]
9-OXO-1,2,3,9-TETRAHYDRO-PYRROLO[2,1-B]QUINAZOLINE-6-CARBOXYLIC ACID
Alanine, 2-methyl-, phenylmethyl ester
2-(2-TRIFLUOROMETHYL-PHENYL)-PYRROLIDINE
(-)-4(R)-(2-Chloro-4-fluorophenyl)-2-(3,5-difluoropyridin-2-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxylic acid methyl ester
2-Butenoic acid, 2-hydroxy-4-[5-(1-Methylethyl)-2,4-bis(phenylMethoxy)phenyl]-4-oxo-, ethyl ester
[4-amino-2-(ethylsulfanyl)pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone
Benzenesulfonamide, 2-[(5-bromo-2-chloro-4-pyrimidinyl)amino]-N-methyl
ALK inhibitor 2
Cefmenoxime hydrochloride
(S)-N-1-Boc-N-4-Cbz-2-piperazinecarboxylic acid
Avermectin
L-CANAVANINE SULFATE
3-Fluoropropiophenone 455-67-4
3-Hydroxypropiophenone 13103-80-5
2-Cyano-5-chloropyrimidine 38275-56-8
N-Formylpiperidine 2591-86-8
Indazole-3-carboxylic acid 4498-67-3
5-Bromo-2-cyanopyrimidine 38275-57-9
4,4-Dibromobenzophenone 3988-03-2
1,2,3,4-Tetrahydro-benzo[b]azepin-5-one 1127-74-8
4038-14-6,(3,4-dimethoxyphenyl)-phenylmethanone 4038-14-6
2-Amino-5-bromopyrimidine 7752-82-1
Triphenylbismuth 603-33-8
3-Ethynylimidazo[1,2-a]pyridine 943320-53-4
4-Nitrophenylacetonitrile 555-21-5
2-(4-aminophenyl)acetonitrile 3544-25-0
isoxazole 288-14-2
5-Methylisoxazole 5765-44-6
3-Aminoisoxazole 1750-42-1
2-Hydroxydiphenylmethane 28994-41-4
2,5-Difluorobenzyl Cyanide 69584-87-8
2,4-Difluorophenylacetonitrile 656-35-9
2,5-Difluorophenylacetic acid 85068-27-5
2,4-Difluorophenylacetic acid 81228-09-3
3-trifluoromethylbenzoic acid 454-92-2
2-[3-(trifluoromethyl)phenyl]acetonitrile 2338-76-3
2-[3-(trifluoromethyl)phenyl]acetic acid 351-35-9
3-Chlorobenzoyl chloride 618-46-2
3-Chlorobenzaldehyde 587-04-2
3-chlorobenzoic acid 535-80-8
3-Chlorobenzyl chloride 620-20-2
3-Chlorobenzyl cyanide 1529-41-5
2-(3-chlorophenyl)acetic acid 1878-65-5
Dimethylchloroacetal 97-97-2
Chloroacetaldehyde diethyl acetal 621-62-5
2-bromo-1,1-diethoxyethane 2032-35-1
2,2-dimethoxyethanamine 22483-09-6
2,2-Diethoxyethylamine 645-36-3
2-Methylphenylacetic acid 644-36-0
3-Isochromanone 4385-35-7
2,5-Dimethylphenylacetic acid 13612-34-5
2,4-Dimethylphenylacetic Acid 6331-04-0
2,5-Dimethylphenylacetonitrile 16213-85-7
2,4-Dimethylphenylacetonitrile 68429-53-8
5-CHLORO-2-FLUOROBENZOYL CHLORIDE 394-29-6
5-Chloro-2-fluorobenzoic acid 394-30-9
2,5-Dichlorobenzaldehyde 6361-23-5
2,5-Dichlorobenzoic acid 50-79-3
2,5-DICHLOROBENZOYL CHLORIDE 2905-61-5
2,2-Azobis(2-methylpropionamidine) dihydrochloride 2997-92-4
L-Phenylalanine, 1-methylethyl ester, hydrochloride 95585-78-7
Diphenylphosphoryl azide 26386-88-9
Methyl 4-(bromomethyl)benzoate 2417-72-3
Tideglusib 865854-05-3
Disodium 7,7-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate) 20324-87-2
SU 6656 330161-87-0
Saccharin 1-methylimidazole 482333-74-4
CeMMEC13 1790895-25-8
Rabusertib 911222-45-2
Salermide 1105698-15-4
EST 88321-09-9
SC79 305834-79-1
KML-29 1380424-42-9
C646 328968-36-1
1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea 182498-32-4
Dp44mT 152095-12-0
Deguelin 522-17-8
PD168393 194423-15-9
YO01027 209984-56-5
DC10539 1822358-25-7
8-OH-DPAT 78950-78-4
YU238259 1943733-16-1
Scriptaid 287383-59-9
Velpatasvir 1377049-84-7
OTX015 202590-98-5
(+)-JQ-1 1268524-70-4
(-)-JQ-1 1268524-71-5
LY 900009 209984-68-9
LY-411575 209984-57-6
(4-nitrophenyl) 4-[bis(1,3-benzodioxol-5-yl)-hydroxymethyl]piperidine-1-carboxylate 1101854-58-3
N,N-dimethyl-2-oxo-1,3-dihydroindole-5-sulfonamide 170565-89-6
5,6,11,12-tetrahydrodibenzo[1,2-b:1,2-g][8]annulene 1460-59-9
Tetraphenylmethane 630-76-2
2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile 284035-33-2
1616380-54-1
N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide 440662-09-9
N-[2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]ethyl]butanamide 932986-18-0
5-(5-(2-(3-aminopropoxy)-6-methoxyphenyl)-1H-pyrazol-3-ylamino)pyrazine-2-carbonitrile 1234015-52-1
3-Methyl-3-[(1E)-2-phenylethenyl]-3,2:5,2:5,3-quaterpyridine 1651890-44-6
3-[4-(Dimethylamino)-3-biphenylyl]-1,1-dimethylure 1469924-27-3
8-Methoxy-N,N-dipropyl-1,2,3,4-tetrahydro-2-naphthalenamine 3897-94-7
4-{4-[(4-{[3-(Acryloylamino)phenyl]amino}-5-fluoro-2-pyrimidinyl) amino]phenoxy}-N-methyl-2-pyridinecarboxamide 1202759-32-7
1,4-Dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)-pyridine-5-carboxylic acid methyl ester 71145-03-4
2-[[3-[[2-(dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N,N-dimethylaniline 500579-04-4
CC-122 1015474-32-4
Bioymifi 1420071-30-2
N-(4-chlorophenyl)-1-(3-(furan-2-yl)benzoyl)piperidine-3-carboxamide 1443437-74-8
E-64C 76684-89-4
2-iodo-6-methoxybiphenyl 84253-78-1
pomalidomide 19171-19-8
Stearoylbenzoylmethane 58446-52-9
benzocaine 94-09-7
tranexamic acid 1197-18-8
lidocaine 137-58-6
lidocaine hydrochloride 73-78-9
Tetracaine hydrochloride 136-47-0
4-(1-phenylethyl)benzene-1,3-diol 85-27-8
Nintedanib 656247-17-5
calcidiol 19356-17-3
β-carotene 7235-40-7
Resazurin sodium salt 62758-13-8
4704-94-3 2-(HYDROXYMETHYL)-1,3-PROPANEDIOL
L-Tyrosine 60-18-4
L-Histidine 71-00-1
3,5-Bis(bromomethyl)toluene 19294-04-3
Bis(4-methylphenyl)methanol 885-77-8
5-Fluoroorotic Acid Hydrate 207291-81-4
1,3,5-Trimethyl-1H-pyrazole-4-carboxylic acid 1125-29-7
5-Amino-2-chloro-4-fluorophenol 84478-72-8
Gabapentin-lactam 64744-50-9
EP-Directory listing
[2-(aminocarbonyl)phenyl]acetic acid 23362-56-3
2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethan-1-ol 103788-65-4
2-Amino-6-cyclopropylamino-9H-purine 120503-69-7
Chromic chloride hexahydrate 10060-12-5
EP-Directory listing 2
Name: Thiacloprid
CAS No: 111988-49-9
PRODUCT DESCRIPTION
【Name】 Thiacloprid 【CAS Registry number】 111988-49-9;111388-49-9 【Synonyms】 3-(6-chloro-3-pyridinylmethyl)-1,3-thiazolidin-2-ylidenecyanamide
Thiaclopyrid
(3-((6-Chloro-3-pyridinyl)methyl)-2-thiazolidinylidene)cyanamide
{(2Z)-3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide
{(2E)-3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide
【Molecular Formula】 C10 H9 ClN4 S
(Products with the same molecular formula) 【Molecular Weight】 252.7233 【Inchi】 InChI=1/C10H9ClN4S/c11-9-2-1-8(5-13-9)6-15-3-4-16-10(15)14-7-12/h1-2,5H,3-4,6H2/b14-10+ 【Canonical SMILES】 C1CSC(=NC#N)N1CC2=CN=C(C=C2)Cl
Chemical and Physical Properties
【Density】 1.424g/cm3 【Melting Point】 136 deg C 【Boiling Point】 423.069°C at 760 mmHg 【Vapour】 0mmHg at 25°C 【Refractive Index】 1.691 【Flash Point】 209.665°C 【Solubilities】 In water, 185 mg/L at 20 deg C 【Color/Form】 Crystals from ether 【Computed Properties】 Molecular Weight:252.72326 [g/mol]
Molecular
Formula:C10 H9 ClN4 S
XLogP3-AA:2.2
H-Bond
Donor:0
H-Bond Acceptor:4
Rotatable Bond Count:2
Exact
Mass:252.023645
MonoIsotopic Mass:252.023645
Topological Polar Surface
Area:77.6
Heavy Atom Count:16
Formal Charge:0
Complexity:324
Isotope
Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter
Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter
Count:0
Covalently-Bonded Unit Count:1
Feature 3D Acceptor
Count:2
Feature 3D Cation Count:2
Feature 3D Ring Count:2
Effective
Rotor Count:2.8
Conformer Sampling RMSD:0.6
CID Conformer
Count:16
Safety and Handling
【Formulations/Preparations】 Granule, flowable concentrate, water dispersible granules.
Tradenames:
Bariard; Calypso; Alanto. 【Octanol/Water Partition Coefficient】 log Kow = 1.26 at 20 deg C 【Disposal Methods】 SRP: The most favorable course of action is to use an alternative chemical
product with less inherent propensity for occupational exposure or environmental
contamination. Recycle any unused portion of the material for its approved use
or return it to the manufacturer or supplier. Ultimate disposal of the chemical
must consider: the material's impact on air quality; potential migration in soil
or water; effects on animal, aquatic, and plant life; and conformance with
environmental and public health regulations.
Environmental Fate and Exposure Potential
【Environmental Fate/Exposure Summary】 TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc
value of 4,700(SRC), determined from a structure estimation method(2), indicates
that thiacloprid is expected to have slight mobility in soil(SRC).
Volatilization of thiacloprid from moist soil surfaces is not expected to be an
important fate process(SRC) given an estimated Henry's Law constant of 1.1X10-14
atm-cu m/mole(SRC), based upon its vapor pressure, 6.0X10-12 mm Hg(3), and water
solubility, 185 mg/L(3). Thiacloprid is not expected to volatilize from dry soil
surfaces(SRC) based upon its vapor pressure(3). A half-life in soil ranging from
0.6 to 3.8 days indicates that biodegradation may be an important environmental
fate process in soil(3).
AQUATIC FATE: Based on a classification scheme(1),
an estimated Koc value of 4,700(SRC), determined from a structure estimation
method(2), indicates that thiacloprid is expected to adsorb to suspended solids
and sediment(SRC). Volatilization from water surfaces is not expected(3) based
upon an estimated Henry's Law constant of 1.1X10-14 atm-cu m/mole(SRC), derived
from its vapor pressure, 6.0X10-12 mm Hg(4), and water solubility, 185 mg/L(4).
According to a classification scheme(5), an estimated BCF of 2(SRC), from its
log Kow of 1.26(4) and a regression-derived equation(6), suggests the potential
for bioconcentration in aquatic organisms is low(SRC). The aquatic aerobic
half-life for thiacloprid ranges from 10-63 days(4).
ATMOSPHERIC FATE:
According to a model of gas/particle partitioning of semivolatile organic
compounds in the atmosphere(1), thiacloprid, which has a measured vapor pressure
of 6.0X10-12 mm Hg at 20 deg C(2), is expected to exist solely in the
particulate phase in the ambient atmosphere. Insufficient data are available to
predict the relative importance or the rate of
photolysis.
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