GW 803430 Basic information |
Product Name: | GW 803430 |
Synonyms: | Thieno[3,2-d]pyrimidin-4(3H)-one, 6-(4-chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy];Thieno[3,2-d]pyrimidin-4(3H)-one, 6-(4-chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-;GW 803430;GW 3430;6-(4-chloro-phenyl)-3-[3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-3H-thieno[3,2-d]pyrimidin-4-one;GW-803430A;6-(4-Chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-thieno[3,2-d]pyrimidin-4(3H)-one;GW-803430 >=98% (HPLC) |
CAS: | 515141-51-2 |
MF: | C25H24ClN3O3S |
MW: | 481.99 |
EINECS: | |
Product Categories: | |
Mol File: | 515141-51-2.mol |
GW 803430 Chemical Properties |
storage temp. | 2-8°C |
solubility | DMSO: ≥4mg/mL at warmed to 60°C |
form | powder |
color | white to beige |
Safety Information |
Hazard Codes | Xn |
Risk Statements | 22-36 |
Safety Statements | 26 |
WGK Germany | 3 |
MSDS Information |
GW 803430 Usage And Synthesis |
Uses | GW 803430 is a melanin-concentrating hormone receptor 1( MCH1) antagonist for treatment of obesity and depression. |
Biochem/physiol Actions | GW-803430 antagonizes central MCHR1 and produces anxiolytic, anti-depressant and anti-obesity effects in rats and mice. It also controls the alcohol-seeking behavior in rats and is a promising treatment for alcohol use-related disorders. |