1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA Basic information |
Product Name: | 1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA |
Synonyms: | Elagolix Impurity 14;1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA;(2-Fluoro-6-trifluoromethyl-benzyl)-urea;elagolix intermediate 3;1-(2-fluoro-6-(trifluoromethyl)benzyl)urea;1-2-Fluoro-6-trifluoromethylbenzyl urea;{[2-fluoro-6-(trifluoromethyl)phenyl]methyl}urea;Eelagolix-2 |
CAS: | 830346-46-8 |
MF: | C9H8F4N2O |
MW: | 236.17 |
EINECS: | |
Product Categories: | |
Mol File: | 830346-46-8.mol |
1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA Chemical Properties |
Boiling point | 268.8±40.0 °C(Predicted) |
density | 1.392±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,Room Temperature |
pka | 12.86±0.46(Predicted) |
Safety Information |
MSDS Information |
1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA Usage And Synthesis |
Uses | 1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development and chemical production processes. |
Chemical Synthesis | In a 250 ml three-necked flask, 3.4 g of E6, 20 ml of water, 4.23 g of urea, and hydrochloric acid (12 mol / L, 2 ml) were added. After refluxing for 3 hours, the reaction solution was cooled to 4 ° C with an ice water bath, and filtered to obtain 3.78 g of a white solid ( Yield: 91%). |
1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA Preparation Products And Raw materials |
Preparation Products | 5-(2-Fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione |