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  • 830346-46-8 1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA
Name:830346-46-8 1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA
CAS No:830346-46-8

PRODUCT DESCRIPTION

1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA Basic information
Product Name: 1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA
Synonyms: Elagolix Impurity 14;1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA;(2-Fluoro-6-trifluoromethyl-benzyl)-urea;elagolix intermediate 3;1-(2-fluoro-6-(trifluoromethyl)benzyl)urea;1-2-Fluoro-6-trifluoromethylbenzyl urea;{[2-fluoro-6-(trifluoromethyl)phenyl]methyl}urea;Eelagolix-2
CAS: 830346-46-8
MF: C9H8F4N2O
MW: 236.17
EINECS:
Product Categories:
Mol File: 830346-46-8.mol
1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA Structure
1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA Chemical Properties
Boiling point  268.8±40.0 °C(Predicted)
density  1.392±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
pka 12.86±0.46(Predicted)
Safety Information
MSDS Information
1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA Usage And Synthesis
Uses 1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development and chemical production processes.
Chemical Synthesis
In a 250 ml three-necked flask, 3.4 g of E6, 20 ml of water, 4.23 g of urea, and hydrochloric acid (12 mol / L, 2 ml) were added. After refluxing for 3 hours, the reaction solution was cooled to 4 ° C with an ice water bath, and filtered to obtain 3.78 g of a white solid ( Yield: 91%).
1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA Preparation Products And Raw materials
Preparation Products 5-(2-Fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione

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