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  • (S)-N4-(3-Chloro-4-fluorophenyl)-7-[(tetrahydrofuran-3-yl)oxy]quinazoline-4,6-diamine  314771-76-1
Name:(S)-N4-(3-Chloro-4-fluorophenyl)-7-[(tetrahydrofuran-3-yl)oxy]quinazoline-4,6-diamine 314771-76-1
CAS No:314771-76-1

PRODUCT DESCRIPTION


Description

Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl is a reactant in the synthesis of Afatinib, an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

Basic Info

Chemical Name (S)-N4-(3-Chloro-4-fluorophenyl)-7-[(tetrahydrofuran-3-yl)oxy]quinazoline-4,6-diamine
Synonyms

QC-4224;N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine;(S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine;4-N-(3-chloro-4-fluorophenyl)-7-[(3S)-oxolan-3-yl]oxyquinazoline-4,6-diamine;

CAS No. 314771-76-1
Molecular Formula C18H16ClFN4O2
Molecular Weight 374.79700
PSA 82.29000
LogP 4.57000

Numbering system

MDL number MFCD18642925

Safety Info

HS Code 2934999090

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