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  • N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine  162012-67-1
Name:N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 162012-67-1
CAS No:162012-67-1

PRODUCT DESCRIPTION


Description

4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline is an intermediate in the synthesis of Afatinib, an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

Basic Info

Chemical Name N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
Synonyms

N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine;

CAS No. 162012-67-1
Molecular Formula C14H7ClF2N4O2
Molecular Weight 336.68100
PSA 83.63000
LogP 4.80940

Numbering system

MDL number MFCD09998825

Properties

Density 1.617 g/cm3
Boiling Point 488.589ºC at 760 mmHg
Flash Point 249.29ºC
Refractive Index 1.707
Vapor Pressure 0mmHg at 25°C

Safety Info

HS Code 2933990090

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