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  • N-[6,6-dimethyl-5-(1-methylpiperidine-4-carbon  718630-59-2
Name:N-[6,6-dimethyl-5-(1-methylpiperidine-4-carbon 718630-59-2
CAS No:718630-59-2

PRODUCT DESCRIPTION


Description

PHA-793887 is a potent CDK (cyclin-dependent kinase) inhibitor. Recent studies shows that PHA-793887 has promising therapeutic activity against acute leukemias in vitro and in vivo. PHA-793887 was used to successfully modulate E2F transcriptional factor-dependent cell cycle, DNA replication, mitosis and apoptosis related gene in both tumors and skin biopsy from patients with solid tumors.

Basic Info

Chemical Name N-[6,6-dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-methylbutanamide
Synonyms

N-(6,6-Dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo(3,4-C)pyrazol-3-yl)-3-methylbutanamide;3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide;

CAS No. 718630-59-2
Molecular Formula C19H31N5O2
Molecular Weight 361.48200
PSA 84.82000
LogP 2.83870

Properties

Density 1.176 g/cm3
Boiling Point 596.226ºC at 760 mmHg
Flash Point 314.386ºC

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