Procaine is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as novocaine. It acts mainly as a sodium channel blocker. Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.
Procaine was first synthesized in 1905, shortly after amylocaine. It was created by the German chemist Alfred Einhorn who gave the chemical the trade name Novocaine, from the Latin nov- (meaning new) and -caine, a common ending for alkaloids used as anesthetics. It was introduced into medical use by surgeon Heinrich Braun. Prior to the discovery of amylocaine and procaine, cocaine was the most commonly used local anesthetic. Einhorn wished his new discovery to be used for amputations, but surgeons preferred general anesthetic. Dentists, however, found it very useful.

Chemical Name	procaine
Synonyms	4-aminobenzoic acid 2-diethylaminoethyl ester;Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester;PROCAINE;
CAS No.	59-46-1
Molecular Formula	C13H20N2O2
Molecular Weight	236.31000
PSA	55.56000
LogP	2.34860

Density	1.077g/cm3
Boiling Point	373.6ºC at 760 mmHg
Melting Point	61ºC
Flash Point	179.8ºC
Refractive Index	1.542

Hazard Class	6.1(b)
HS Code	2922499100
Packing Group	III
RIDADR	UN 3249