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  • 4-Chloro-3-(trifluoromethyl)phenyl isocyanate  327-78-6
Name:4-Chloro-3-(trifluoromethyl)phenyl isocyanate 327-78-6
CAS No:327-78-6

PRODUCT DESCRIPTION


Description

4-Chloro-3-(trifluoromethyl)phenyl isocyanate is used as a reagent to synthesize pyrimidinylaminobenzene derivatives, compounds that have antiproliferative activity against melanoma cell lines. 4-Chloro-3-(trifluoromethyl)phenyl isocyanate is also used to synthesize α-thymidine analogues that act as antimalarial agents.

Basic Info

Chemical Name 4-Chloro-3-(trifluoromethyl)phenyl isocyanate
Synonyms

4-Chloro-3-(trifluoromethyl)phenyl Isocyanate;Sorafenib intermediate 3;Isocyanic Acid 4-Chloro-3-(trifluoromethyl)phenyl Ester;1-chloro-4-isocyanato-2-trifluoromethylbenzene;3-TRIFLUOROMETHYL-4-CHLORO-PHENYL ISOCYANATE;4-Cl-3CF3-phenyl isocyanate;1-chloro-4-isocyanato-2-(trifluoromethyl)benzene;4-Chloro-3-(trifluoromethyl)phenylisocyanate;Collapse

CAS No. 327-78-6
Molecular Formula C8H3ClF3NO
Molecular Weight 221.56400
PSA 29.43000
LogP 3.32610

Properties

Appearance & Physical State white to yellowish low melting solid, powder or chunks
Density 1.4 g/cm3
Boiling Point 86-90ºC (14 mmHg)
Melting Point 35-36ºC
Flash Point 99ºC
Refractive Index 1.487

Safety Info

Hazard Class 6.1
Safety Statements S26-S36/37/39
HS Code 2929109000
Packing Group III
WGK Germany 3
RIDADR UN 2206
Risk Statements R20/21/22; R36/37/38
Hazard Codes Xn

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