Welcome to our website!

Product Catalog

Rapid Product Index

Recommended Products

Friend Links

  • Prucalopride  179474-81-8
Name:Prucalopride 179474-81-8
CAS No:179474-81-8

PRODUCT DESCRIPTION


Description

Prucalopride (brand name Resolor, developed by Johnson & Johnson and licensed to Movetis) is a drug acting as a selective, high affinity 5-HT4 receptor agonist which targets the impaired motility associated with chronic constipation, thus normalizing bowel movements. Prucalopride was approved for use in Europe in 2009, in Canada (named Resotran) on December 7, 2011 and in Israel in 2014 but it has not been approved by the Food and Drug Administration for use in the United States. The drug has also been tested for the treatment of chronic intestinal pseudo-obstruction.

Basic Info

Chemical Name Prucalopride
Synonyms

4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide;Resolor;Unii-0A09iuw5tp;

CAS No. 179474-81-8
Molecular Formula C18H26ClN3O3
Molecular Weight 367.87000
PSA 76.82000
LogP 2.99780

Properties

Density 1.28g/cm3
Boiling Point 481.4ºC at 760mmHg
Flash Point 244.9ºC
Refractive Index 1.599
Vapor Pressure 2E-09mmHg at 25°C

RELATED PRODUCTS