Alitame is an aspartic acid-containing dipeptide sweetener. It was developed by Pfizer in the early 1980s and currently marketed in some countries under the brand name Aclame. Most dipeptides are not sweet, but the unexpected discovery of aspartame in 1965 led to a search for similar compounds that shared its sweetness. Alitame is one such second-generation dipeptide sweetener. Neotame, developed by the owners of the NutraSweet brand, is another.
Alitame is about 2000 times sweeter than sucrose (table sugar), about 10 times sweeter than aspartame, and has no aftertaste. Its half-life under hot or acidic conditions is about twice as long as aspartame's, although some other artificial sweeteners, including saccharin and acesulfame potassium, are more stable yet. Unlike aspartame, alitame does not contain phenylalanine, and can therefore be used by people with phenylketonuria.
Alitame has approved for use in Mexico, Australia, New Zealand and China. Danisco has withdrawn its petition for using alitame as a sweetening agent or flavoring in food in USA.

Chemical Name	(3S)-3-amino-4-oxo-4-[[(2R)-1-oxo-1-[(2,2,4,4-tetramethylthietan-3-yl)amino]propan-2-yl]amino]butanoic acid
Synonyms	(S)-3-Amino-4-oxo-4-(((R)-1-oxo-1-((2,2,4,4-tetramethylthietan-3-yl)amino)propan-2-yl)amino)butanoic acid;3-(L-Aspartyl-D-alaninamido)-2,2,4,4-tetramethylthietane;L-aspartyl-D-alanine 2,2,4,4-tetramethylthietanylamide;UNII-PCE8DAE750;Alitame;
CAS No.	80863-62-3
Molecular Formula	C14H25N3O4S
Molecular Weight	331.43100
PSA	146.82000
LogP	1.56400

Density	1.25g/cm3
Boiling Point	608.5ºC at 760 mmHg
Flash Point	321.8ºC
Refractive Index	1.559

HS Code	2934999090