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  • benzbromarone  3562-84-3
Name:benzbromarone 3562-84-3
CAS No:3562-84-3

PRODUCT DESCRIPTION


Description

Benzbromarone (INN) is a uricosuric agent and non-competitive inhibitor of xanthine oxidase used in the treatment of gout, especially when allopurinol, a first-line treatment, fails or produces intolerable adverse effects. It is structurally related to the antiarrhythmic amiodarone.
Benzbromarone is highly effective and well tolerated, and clinical trials as early as 1981 and as recently as April 2008 have suggested it is superior to both allopurinol, a xanthine oxidase inhibitor but not uricosuric, and probenecid, another uricosuric drug.

Basic Info

Chemical Name benzbromarone
Synonyms

Hipurik;Normurat;Benzbromarone;Desuric;Benzbromaron;Narcaricin;3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethylbenzofuran;(3,5-dibromo-4-hydroxyphenyl)(2-ethylbenzofuran-3-yl)methanone;(3,5-dibromo-4-hydroxyphenyl)-(2-ethyl-3-benzofuranyl) methanone;Minuric;2-Ethyl-3-(3,5-dibromo-4-hydroxybenzoyl)benzofuran;(3,5-dibromo-4-hydroxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone;Exurate;Urinorm;Uricovac;Collapse

CAS No. 3562-84-3
Molecular Formula C17H12Br2O3
Molecular Weight 424.08300
PSA 50.44000
LogP 5.45680

Properties

Appearance & Physical State White to off-white crystalline powder
Density 1.709 g/cm3
Melting Point 161 - 163ºC
Flash Point 264.7ºC
Storage Condition 2-8ºC

Safety Info

Hazard Class 6.1(b)
Safety Statements S36
HS Code 2932190090
Packing Group III
RIDADR UN 2811
Risk Statements R22
Hazard Codes Xn

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