1.Identification

1.1GHS Product identifier

1.2Other means of identification

1.3Recommended use of the chemical and restrictions on use

1.4Supplier's details

1.5Emergency phone number

2.Hazard identification

2.1Classification of the substance or mixture

Acute toxicity - Oral, Category 4

Skin irritation, Category 2

Eye irritation, Category 2

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3

2.2GHS label elements, including precautionary statements

Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H412 Harmful to aquatic life with long lasting effects
Precautionary statement(s)
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection. P273 Avoid release to the environment.
Response	P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/…if you feel unwell. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P313 If skin irritation occurs: Get medical advice/attention. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313 If eye irritation persists: Get medical advice/attention.
Storage	none
Disposal	P501 Dispose of contents/container to ...

2.3Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1Substances

4.First-aid measures

4.1Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.

In case of skin contact

First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer for medical attention .

In case of eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

If swallowed

Rinse mouth. Do NOT induce vomiting. Rest. Refer for medical attention .

4.2Most important symptoms/effects, acute and delayed

SYMPTOMS: Symptoms of exposure to this compound may include eye and mucous membrane irritation. It can cause contact dermatitis, conjunctivitis, exacerbation of seborrhea and acne vulgaris. Eye contact may result in a smarting sensation. Ingestion of this material can cause central nervous system disturbances. Symptoms resulting from exposure to this compound include disorientation, staggering gait, slurred speech, crying out, episodes consisting of stiffening into a sitting position, extending of extremities, flexing of the fingers and dorsiflexing the toes. It may also cause jaundice, aplastic anemia, bleeding, convulsive seizure or death. It may irritate tender areas of the skin. It may also cause severe eye injury. Other symptoms are desquamation about the nose, dryness of face, a slight tingling sensation and a bullous eruption in the antecubital fossae. Irritation of the gastro-intestinal tract and coma are possible. It may cause purpuric or ecchymotic areas. ACUTE/CHRONIC HAZARDS: This compound is irritating to the skin, eyes and mucous membranes. When heated to decomposition it emits toxic fumes of carbon monoxide, carbon dioxide and nitrogen oxides. It may be harmful by inhalation or ingestion.

4.3Indication of immediate medical attention and special treatment needed, if necessary

Decontaminate the skin with soap and water ... . Eye contamination should be removed by prolonged flushing of the eye with copious amounts of clean water or saline. If irritation persists, specialized medical treatment should be obtained. Topical steroids and oral antihistamines have been used for severe skin reactions that occasionally follow application of DEET.

5.Fire-fighting measures

5.1Extinguishing media

Suitable extinguishing media

Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2Specific hazards arising from the chemical

This chemical is combustible.

5.3Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2Environmental precautions

Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Personal protection: complete protective clothing including self-contained breathing apparatus.

6.3Methods and materials for containment and cleaning up

ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up: Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal.

7.Handling and storage

7.1Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2Conditions for safe storage, including any incompatibilities

Separated from strong oxidants, acids, organic nitro compounds and food and feedstuffs. Keep in a well-ventilated room.Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

8.Exposure controls/personal protection

8.1Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

10.Stability and reactivity

10.1Reactivity

no data available

10.2Chemical stability

Stable under recommended storage conditions.

10.3Possibility of hazardous reactions

The vapour is heavier than air.N,N-DIETHYL-M-TOLUAMIDE is incompatible with strong acids, strong bases and strong oxidizing agents. It hydrolyzes slowly in the presence of water. It has a solvent effect on most plastics, paints, and varnishes. It is also incompatible with rayon, acetate or dynel clothing.

10.4Conditions to avoid

no data available

10.5Incompatible materials

Incompatible materials: Strong oxidizing agents, strong acids, strong bases, strong reducing agents

10.6Hazardous decomposition products

When heated to decomposition it emits toxic fumes of /nitrogen oxides/.

11.Toxicological information

Acute toxicity

• Oral: LD50 Rat oral 1892 mg/kg
• Inhalation: LC50 Rat inhalation >4100 mg/cu m/4 hr
• Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

EPA: Not classifiable as to human carcinogenicity. IARC: Not evaluated. NTP: Not evaluated

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1Toxicity

• Toxicity to fish: LC50; Species: Pimephales promelas (fathead minnow); Conditions: freshwater, flow through, 25°C, pH 7.3, hardness 45.0 mg/L CaCO3, alkalinity 47.0 mg/L CaCO3, dissolved oxygen 6.1 mg/L; Concentration: 110000 ug/L for 96 hr (95% confidence interval: 106000-114000 ug/L) /98% purity
• Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water Flea) age <24 hr neonate; Conditions: freshwater, renewal, 19.4-20.3°C, pH 8.2-8.6, hardness 134-136 mg/L CaCO3, alkalinity 179-182 mg/L CaCO3, dissolved oxygen > or =7.7 mg/L; Concentration: 24000 ug/L for 21 days (95% confidence interval: 21000-27000 ug/L); Effect: reproduction, decreased progeny counts/numbers /98.68% purity
• Toxicity to algae: no data available
• Toxicity to microorganisms: no data available

12.2Persistence and degradability

AEROBIC: DEET, present at 100 mg/L, did not biodegrade in 4 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI(1). However, in a OECD 301B test DEET was shown to biodegrade 83.8% in 4 weeks using activated sewage sludge and measuring carbon dioxide produced(2). DEET reached 30% and 37% of the theoretical oxygen demand and chemical oxygen demand after 7 days in another test, but biodegradation seemed to halt after reaching 40 and 48%, respectively(2). DEET was shown to biodegrade using Po River water, forming three transformation products(3). Pseudomonas putida DTB (isolated from activated sludge from a municipal wastewater treatment plant in Ithaca, NY) degraded DEET to 3-methylbenzoate and diethylamine under aerobic conditions(4).

12.3Bioaccumulative potential

BCF values of <2.4 and 0.8-2.4 were measured using carp (Cyprinus carpio) which were exposed to 0.05 and 0.50 mg/L of DEET, respectively, over a 6-week period(1). According to a classification scheme(2), these BCF values suggest the potential for bioconcentration in aquatic organisms is low(SRC).

12.4Mobility in soil

Using a structure estimation method based on molecular connectivity indices(1), the Koc of DEET can be estimated to be 115(SRC). According to a classification scheme(2), this estimated Koc value suggests that DEET is expected to have moderate mobility in soil.

12.5Other adverse effects

no data available

13.Disposal considerations

13.1Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1UN Number

14.2UN Proper Shipping Name

14.3Transport hazard class(es)

14.4Packing group, if applicable

14.5Environmental hazards

14.6Special precautions for user

no data available

14.7Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1Safety, health and environmental regulations specific for the product in question